OOGENESIS IN MAMMALS Oogenesis is the process by which female germ cells (oogonia) undergo a series of cell divisions and differentiations to produce mature eggs (ova or oocytes). This complex process takes place in the ovaries of mammals and is crucial for reproductive success. Oogenesis involves several stages, from the development of primordial germ cells to the formation of mature eggs ready for fertilization. Here is an overview of the key stages of oogenesis in mammals: 1. Formation of Primordial Germ Cells (PGCs): Occurs during early embryonic development. PGCs arise from a subset of cells in the embryonic epiblast. Migrate to the genital ridge and undergo mitotic divisions. 2. Differentiation into Oogonia: PGCs differentiate into oogonia. Oogonia undergo mitotic divisions to increase their numbers. 3. Formation of Primordial Follicles: Oogonia develop into primary oocytes. Surrounding somatic cells (pre-granulosa ...