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Showing posts with the label GK & GS

CAR T-Cell Therapy

India has made a significant advancement in cancer treatment with the introduction of CAR T-cell therapy, showing promising results in recent clinical trials published in The Lancet.   Here's a simplified explanation: What is CAR T-cell therapy? A new type of cancer treatment that uses the patient's own immune system.   T-cells (a type of white blood cell) are collected from the patient's blood.   In a lab, these T-cells are genetically modified to attack cancer cells.   The modified T-cells are then infused back into the patient.   What types of cancer does it treat? Certain blood cancers, especially when other treatments have failed.   What were the results of the clinical trials? Nearly 73% of patients responded positively to the treatment. The trials also provided important data on survival rates for patients with acute lymphoblastic leukemia and lymphoma. Is it available in India? Yes, India's drug regulator approved the ...

Survival Strategies of Antarctic Midge

The Antarctic midge, Belgica antarctica , is a tiny insect that's incredibly important because it's the only insect native to Antarctica. It's uniquely adapted to survive in the continent's harsh environment, and scientists are studying it to understand how climate change might affect it. Here's a simplified explanation: What's special about the Antarctic midge? It's the only insect that lives its entire life cycle in Antarctica. How does it survive the extreme cold? It has two main survival strategies: Quiescence: A short-term dormancy, like hitting the "pause" button when conditions get bad. The midge can quickly become active again when things improve. Obligate Diapause: A longer, pre-planned dormancy that happens every year before winter. This is like hitting the "hibernate" button. It helps the midge store up energy and find a good place to spend the winter. What's the difference between quiescence and obligate diapause?...

What IS USAID

USAID, the United States Agency for International Development, is the main US government agency that gives aid to other countries. Recently, there's been a debate about whether it should continue to exist.   Here's a simplified explanation: What is USAID? The US government's main organization for giving aid to other countries.   When was it created? 1961, by President John F. Kennedy.   What does it do? It focuses on things like: Helping countries recover from disasters.   Reducing poverty. Promoting democracy.   It played a big role in US foreign policy, especially during the Cold War.   How much money does it spend? In 2023, USAID spent $72 billion on aid around the world. This money goes to things like health programs, clean water, and energy.   Who gets the most aid? In 2023, Ukraine received the most aid ($14.4 billion), followed by Jordan, Yemen, and Afghanistan. How much of all global aid comes from USAID?...

The skeletal system

Overview The skeletal system is essentially your body's framework. It is made up of all your bones and the tissues that support and connect them (like cartilage, ligaments, and tendons). Sometimes it’s called the musculoskeletal system because it works closely with your muscles to help you move, protect your internal organs, produce blood cells, and store important minerals. Key Functions Support and Shape: Your bones give your body its structure and shape, allowing you to stand upright and move. They act like a scaffold, supporting the soft tissues and organs. Movement: Bones, in combination with muscles, joints, and connective tissues (tendons and ligaments), allow for movement. Muscles attach to bones via tendons and, when they contract, pull on the bones to produce motion at the joints. Protection: The skeletal system protects vital organs. For example, the skull protects the brain, the rib cage shields the heart and lungs, and the vertebrae protect the spinal cord. Blood Cell ...

Reproductive system

Overview of the Human Reproductive System The human reproductive system is the collection of organs and tissues that work together to produce offspring. It plays a critical role in continuing the species by producing the cells needed for reproduction (gametes), supporting fertilization, and nurturing the developing embryo in females. Key Functions Production of Gametes: In males, the testes produce sperm. In females, the ovaries produce eggs (ova). These specialized cells carry half of the genetic information needed for a new individual. Hormone Production: Both male and female reproductive systems produce hormones (like testosterone, estrogen, and progesterone) that regulate sexual development, fertility, and secondary sexual characteristics (such as facial hair in men and breast development in women). Fertilization: In sexual reproduction, a sperm cell from the male meets an egg from the female. In females, fertilization typically occurs in the fallopian tube. Once fertilized, the eg...

Central Nervous System

  Overview The human nervous system is the body’s control and communication network. It lets you sense changes (stimuli) in your environment—like sound, light, or heat—and quickly react (response) so you can protect yourself or take advantage of new opportunities. In everyday life, this means you feel pain when you burn your finger, which warns you to stop the harm. How It Works Your nervous system sends signals between your brain and the rest of your body. These signals are carried by special cells called neurons, which act like messengers using electrical and chemical signals. Major Parts of the Human Nervous System Central Nervous System (CNS): Brain: The brain is the most complex part of your nervous system. It’s where thinking, decision-making, and coordination of body functions occur. It controls everything from your movements and emotions to vital functions like breathing, heart rate, and temperature regulation. The brain itself is divided into three major parts: Forebrain: ...

Circulatory System

Overview The human circulatory system is like a complex transportation network that keeps every cell in your body supplied with what it needs—and it takes away waste too. It does this by moving blood, which carries oxygen, nutrients, hormones, and other essential substances, all throughout your body. Key Components and Their Roles The Heart: The heart is a strong, muscular pump located in your chest. It has four chambers (two upper atria and two lower ventricles) that work together to keep blood moving. The heart’s pumping action creates two separate loops (known as double circulation): one loop sends deoxygenated blood to the lungs to pick up oxygen, and the other loop distributes the oxygen-rich blood to the rest of your body. Blood: Blood is the fluid that carries oxygen, nutrients, and hormones to your cells. It also collects waste products like carbon dioxide, which are later removed from the body. Blood is made up of plasma (mostly water), red blood cells (which carry oxygen), wh...

Respiratory System

Overview The human respiratory system is the network of organs and tissues that lets you breathe. Its main job is to bring oxygen into your body and remove carbon dioxide. This process of gas exchange keeps your cells powered and your body working properly. Main Parts and What They Do Nose and Mouth: Nose: Air enters through your nostrils. Inside the nose, tiny hairs and mucus trap dust and germs, while blood vessels warm and moisten the air. Mouth: Air can also be taken in through the mouth, especially during heavy breathing. Pharynx (Throat): This is a wide, hollow passage that serves as a common route for both air and food. It helps direct food into the esophagus and air into the lungs. Larynx (Voice Box): Located in the front of the neck, the larynx contains the vocal cords. These cords vibrate when air passes through them to produce sound. A small flap called the epiglottis covers the windpipe during swallowing so that food does not go into the lungs. Trachea (Windpipe): The tra...