Introduction to EMBL (European Molecular Biology Laboratory)
The European Molecular Biology Laboratory (EMBL) is an international research organization in the field of molecular biology. EMBL operates several sites across Europe, each focusing on different aspects of molecular biology research and services.
Centers of EMBL
EMBL Heidelberg (Germany)
Main laboratory and headquarters.
Focuses on a broad range of molecular biology.
Provides core facilities and services to support scientific research.
EMBL-EBI (Hinxton, UK)
European Bioinformatics Institute.
Specialize in bioinformatics and computational biology.
Manages vast databases of biological data, including genomics, proteomics and more.
Provides bioinformatics tools and resources for the global scientific community.
EMBL Grenoble (France)
Located in the European Photon and Neutron (EPN) Science Campus.
Focuses on structural biology using X-Ray crystallography and cryo-electron microscopy.
Collaborates with other institutes on large-scale structural biology projects.
EMBL Hamburg (Germany)
Situated at the Deutsches Elektronen-Synchrotron (DESY) campus.
Specializes in structural biology using synchrotron radiation.
Provides advanced facilities for macromolecular crystallography and small-angle X ray scattering.
EMBL Rome (Italy)
Focuses on epigenetics, neurobiology and developmental biology.
Conduct research on how genes are regulated and how they influence organism development.
EMBL Barcelona (Spain)
Concentrates on tissue biology and disease modeling.
Develops new methods to study tissues and organ development.
Works on regenerative medicine and cancer research.
Services offered by EMBL
European Nucleotide Archive (ENA)
Repository for nucleotide sequences.
Facilitates submission and retrieval of sequence data.
EMBOSS Transeq
Translates nucleotide sequences into protein sequences.
Supports 6 open reading frames (3 forward, 3 reverse).
EMBOSS Sixpack
Translates nucleotide sequences in all six reading frames.
Identifies potential protein-coding regions.
EMBOSS Backtranseq
Predicts DNA sequences from protein sequences.
Useful for designing primers and other genetic tools.
Clustal Omega
Tool for multiple sequence alignment.
Allows alignment of many sequences simultaneously.
ChEMBL
Database of bioactive molecules with drug-like properties.
Integrates chemical, bioactivity, and genomic data for drug discovery.
ChEBI
Database of chemical entities.
Provides reference chemical structures, nomenclature, and classification.
BioSample
Database of biological sample metadata.
Facilitates data sharing and integration across studies.
EMMA
European Mouse Mutant Archive.
Repository of mouse models for scientific research.
Europe PMC
Comprehensive database of life science literature.
Contains over 44 million articles and preprints for research access.
These services support a wide range of scientific research and innovation in molecular biology and related fields.