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Showing posts from November, 2023

ANTIGEN-ANTIBODY INTERACTIONS

  ANTIGEN-ANTIBODY INTERACTIONS Now, to understand this concept, we first need to recap what antigens and antibodies are. Antigens : An antigen is a molecule or a molecular structure that is recognized by the immune system as foreign or non-self. Antigens can be found on the surface of pathogens such as bacteria, and viruses, and even on the surface of abnormal cells like cancer cells. They can also be substances like pollen or dust that trigger allergic responses. These antigens are like "red flags" that alert our immune system to potential threats. Antibodies : Antibodies, also known as immunoglobulins, are Y-shaped proteins produced by white blood cells known as B cells. They are a crucial part of our immune system's defence mechanism. Each antibody is specific to a particular antigen, and it's like a lock and key system. When an antibody encounters its matching antigen, it can bind to it with high precision. Now, let's explore how antigen-antibody in...

Antigenicity and immunogenicity

Antigenicity and Immunogenicity: Unraveling the Language of the Immune System Antigenicity and immunogenicity are two related but distinct concepts in immunology that describe the ability of a substance to interact with the immune system. Let's explore these terms: ANTIGENICITY Antigenicity refers to the property of a substance (an antigen) to be recognized and interact with the immune system, specifically with antibodies or immune cells such as T cells. An antigen is any molecule or molecular structure that can be recognized by the immune system as foreign or non-self. Antigens can include components of pathogens (like proteins on the surface of a virus), allergens (substances that trigger allergic reactions), or even molecules on the surface of our own cells that are recognized as abnormal. Key points about antigenicity: ·         Antigenicity is the ability of a substance to be recognized by the immune system. ·     ...

ANTIGENS: STRUCTURE, FUNCTION AND DIVERSITY

  STRUCTURE Antigens are substances that can trigger an immune response in the body. They can be components of pathogens (like bacteria or viruses), foreign proteins, or even parts of our own cells that are recognized as abnormal. The structure of antigens varies widely because they can be virtually anything that the immune system can recognize as foreign. However, here are some common characteristics of antigens: Proteins and Glycoproteins:  Many antigens are proteins or glycoproteins, which are proteins with attached carbohydrate molecules. These include viral proteins, bacterial cell surface proteins, and some allergenic proteins Carbohydrates:  Some antigens are carbohydrates or glycolipids, like those found on the surface of bacteria or the ABO blood group antigens on red blood cells. Peptides and Epitopes:  Antigens often contain specific regions called epitopes or antigenic determinants. These are the parts of the antigen tha...

Antibodies: Structures, functions and diversity

STRUCTURE Antibodies, also known as immunoglobulins, are Y-shaped proteins produced by B cells of the immune system. They play a critical role in the immune response by recognizing and neutralizing specific pathogens, such as bacteria and viruses. Antibodies have a well-defined structure that allows them to perform their functions effectively. Let's break down the structure of antibodies: BASIC STRUCTURE OF ANTIBODIES Y-Shaped Molecule: Antibodies have a Y-shaped structure, often depicted as two "arms" and a "stalk." This Y-shape is formed by four polypeptide chains. Four Polypeptide Chains: Antibodies consist of two identical heavy chains (H) and two identical light chains (L). These chains are held together by disulfide bonds and are organized into two identical arms. Variable and Constant Regions: Each antibody has two main regions in its structure: the variable region and the constant region. Variable Region: ...

Menstrual Cycle

Understanding the Menstrual Cycle: A Monthly Journey Today, we're going to delve into the intricacies of the menstrual Cycle, a fundamental aspect of reproductive biology in individuals with a female reproductive system.  This cycle is like a monthly journey that the female body undergoes and it plays a pivotal role in fertility and overall health.  What is the Menstrual Cycle? The menstrual cycle is a natural, recurring process that occurs in the bodies of individuals with a female reproductive system. It involves a series of changes in the female reproductive organs and hormones, typically lasting around 28 days, although it can vary from person to person. Key Phrases of the Menstrual Cycle: The menstrual cycle can be divided into several key stages: Menstruation (Day 1 - 5): The cycle begins with menstruation, commonly known as a period. During this phase, the lining of the uterus (endometrium) is shed and exits the body through the vagina. This phrase marks the start of a ...

The Central Dogma of life

The Central Dogma of Molecular Biology: Unraveling the Blueprint of Life Hello! Today, we're diving into a foundational concept that underpins our understanding of how genetic information is transmitted within living organisms. It's called the Central Dogma of Molecular Biology. 1. Cracking the Code: DNA to RNA Our story begins with DNA, the intricate molecule carrying the genetic instructions for building and maintaining life. The first step in the Central Dogma is the transcription of DNA into RNA. During transcription, a specific segment of DNA serves as a template to produce a complementary RNA molecule. DNA (Deoxyribonucleic Acid): This marvellous molecule resides in the cell nucleus. It holds the complete set of instructions, like an elaborate script for the production of proteins. RNA (Ribonucleic Acid): RNA is the intermediary messenger that carries the genetic information from the nucleus to the protein...